These are the main characters of the game and in bracets the voice actor's name, click the picture for full Bio

David/Solid Snake/Lieutenant Junior Grade:Iriquois Pliskin (David Hayter)

Olga Gurlukovich (Vanessa Marshall)

Vamp (Phil LaMarr)

Emma Emmerich-Danziger/E.E (Jennifer Hale)

Colonel:Roy Campbell/Chicken Fox (Paul Eiding)

Helena Dolph Jackson/Lady Luck/Fortune/Queen (Maula Gale)

(Your Name)/Jack/Raiden/White Devil/Jack The Ripper/Snake/Carrier Boy (Quinton Flynn)

David/Lieutenant Junior Grade:Iriquois Pliskin/Solid Snake (David Hayter)

Fatman/The Emperior of Explosives (Barry Dennen)

General:Ivan/Crazy Ivan/Revolver Ocelot/ Shalashaska (Patrick Zimmerman)

Olga Gurlukovich/Mr. X/Deepthroat (Vanessa Marshall)

The Patriots/The La-Li-Lu-Le-Lo/The Wisemen's Committee

EX President:George Sears/Solidus Snake/Solid Snake/King (John Cygan)

Marine Commandant: Scott Dolph (Kevin Richardson)

Colonel:Sergei Gurlukovich (Earl Boen)

Dr.Hal Emmerich/Otacon (Christopher Randolph)

President:James Johnson (Paul Lukather)

Ex President:George Sears/Solidus Snake/Solid Snake/King (John Cygan)

Peter Stillman/Peg-Legged-Peter (Greg Eagles)

Rosemary (Lara Cody)

Colonel:Richard Ames (Pete Renaday)

Emma's Parrot/"Noisy Overgrowned Parakeet"

Frank Jeager/Gray Fox/Deepthroat (Mentioned)

Sniper Wolf (Mentioned)

Vulcan Raven (Mentioned)

Liquid Snake/Ocelot's Right Arm (Cam Clarke)

Johnny Sasaki (Voice Appearance by Dean Scofield)

Meryl Silverburgh (Mentioned)

Saladin/Big Boss/Vermon CaTaffy (Mentioned)

Mei Ling (Voice Appearance by Kim Mai Guest )